Publications

 

2024:

 

6. Wireless microLED packed beds for scalable continuous multiphasic photochemistry

Lopez, E. D.; Musacchio, P. Z.; Teixeria, A. R.

Reaction Chemistry & Engineering 2024, 9, 2963-2974.

https://doi.org/10.1039/D4RE00241E

2023:

 

5. Azolation of Benzylic C–H Bonds via Photoredox-Catalyzed Carbocation Generation

Das, M.; Zamani, L.; Bratcher, C.; Musacchio, P. Z.

Journal of American Chemical Society 2023, 145, 3861–3868.

https://doi.org/10.1021/jacs.2c12850

 

4. Shining light on diselenide bonds

Fitzpatrick, N. A.; Musacchio, Z. P.

Nature Chemistry 2023, 15, 163–164.

Nature Chemistry ‘News & Views’ for Nat. Comm. 202213, 6885.

2022:

3. A “one size fits all” ligand for photoredox and metallaphotoredox catalysis

Zamani, L.; Musacchio, Z. P.

Chem 2022, 8, 9, 2324–2326.

Preview for Chem 2022, 8, 9, 2419–2431.

 

2. A SN1 mechanistic approach to the Williamson ether reaction via photoredox

catalysis applied to benzylic C(sp3)–H bonds

Fitzpatrick, N. A.; Zamani, L.; Das, M.; Yayla, H. G.; Lall, M. S.; Musacchio, P. Z.

Tetrahedron 2022, 125, 132986

https://doi.org/10.1016/j.tet.2022.132986

~ 2022 Editors' Choice Collection

 
 
 
Screen+Shot+2021-02-25+at+3.44.36+PM.jpg
 
 

1. A Photoredox-Catalyzed Approach for Formal Hydride Abstraction to Enable a General Csp3–H Functionalization with nucleophilic partners (F, C, O, N, and Br/Cl)

Zhang, Y.; Fitzpatrick, N. A.; Das, M.; Bedre, I.; Yayla, H. G.; Lall, M. S.; Musacchio, P.Z.

Chem. Catalysis 2022, 2, 292-308.

https://doi.org/10.1016/j.checat.2021.12.010

(PDF)

~highlighted by Dr. Thomas West in Nature Synthesis: “Removing Hydride”

~preview by G. A. Lutovsky and T. P. Yoon in Chem Catalysis: “A radical crossover into C–H functionalization”

~highlighted in Synform 2022: link

~featured on the cover of Chem Catalysis: link

 
 
 
 

Prior to WPI:

 
 

8. Profiling the proteome-wide selectivity of diverse electrophiles. P.R.A. Zanon, F. Yu, P.Z. Musacchio, L. Lewald, M. Zollo, K. Krauskopf, D. Mrdović, P. Raunft, T.E. Maher, M. Cigler, C. J. Chang, K. Lang, F.D. Toste, A.I. Nesvizhskii, S.M. Hacker. ChemRxiv. Preprint. https://doi.org/10.33774/chemrxiv-2021-w7rss-v2 Link

7. Metallaphotoredox aryl and alkyl radiomethylation for PET ligand discovery. R.W. Pipal, K.T. Stout, P.Z. Musacchio, S. Ren, T.J.A. Graham, S. Verhoog, L. Gantert, T.G. Lohith, A. Schmitz, H.S. Lee, D. Hesk, E.D. Hostetler, I.W. Davies, D.W.C. MacMillan, Nature 2021, 589, 542-547. Link

6. A Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation A. H. Christian, S. Jia, W. Cao, P. Zhang, A. T. Meza, M. S. Sigman, C. J. Chang, F. D. Toste, J. Am. Soc. 2019, 141, 0052. Link

5. A Radical Approach to the Copper Oxidative Addition Problem: Trifluoromethylation of Bromoarenes C.C. Le, T. Q. Chen, T. Liang, P. Zhang, D. W. C. MacMillan, Science 2018, 360, 1010. Link

 

 

4. The merger of transition metal and photocatalysis (Review). J.R. Twilton, C. C. Le, P. Zhang, M. H. Shaw, R. W. Evans, D. W. C. MacMillan, Nat. Rev. Chem. 2017, 1, 0052. Link

 

3. Silyl Radical Activation of Alkyl Halides in Metallaphotoredox Catalysis: A Unique Pathway for Cross Electrophile Coupling P. Zhang, C. C. Le, D. W. C. MacMillan, J. Am. Chem. Soc. 2016, 138, 8084. Link

 

 

2. Concise Approach to 1,4-Dioxygenated Xanthones via Novel Application of the Moore Rearrangement A. L. Nichols, P. Zhang, S. F. Martin, Tetrahedron 2012, 68, 7591. Link

1. General and Expedient Synthesis of 1,4-Dioxygenated Xanthones A. L. Nichols, P. Zhang, S. F. Martin, Org. Lett. 2011, 13, 4696. Link