Musacchio Research Group

Synthetic Chemistry · Chemical biology · Radical Intermediates

 
 
 
 

Interfacing Organic Chemistry and Chemical Biology

In order to address the complex and dynamic challenges facing society in the area of disease detection, treatment and prevention, an interdisciplinary approach must be taken for more innovative solutions. The Musacchio research group aims to develop new chemical technologies that will assist in the synthesis and design of next-generation drug molecules, chemotherapeutics, and biologics. We seek to expand the utility of radical chemistry at the intersection of synthetic organic chemistry and chemical biology through new reaction development, bioconjugation strategies, and biocatalysis.

 

Contact

Location

Gateway Park, WPI

60 Prescott St
Worcester, MA 01605
 

Contact Info

pzmusacchio@wpi.edu
(508)831-6604

 

Funding Sources

We appreciate financial support from Pfizer, ACS PRF, and NIH!


 

Group News

October 2022: Patti receives the Leonard P. Kinnicutt Professorship

Prof. Musacchio receives an endowed professorship from WPI! link

 

October 2022: Our group publishes their second research paper in Tetrahedron

Congratulations to Nick, Mrinmoy, Leila, Hattie and Manj! The work was part of our collaboration with Pfizer.

 

July 2022: NIH MIRA Outstanding Investigator Award

The Musacchio lab receives an NIH MIRA R35 award to support our continued efforts in formal hydride abstraction!

 

May 2022: ACS PRF Doctoral New Investigator Grant

Our group received its first funding from the ACS!

 

January 2022: First Publication OUt!

Our group’s first research paper is published in Chem Catalysis. Check it out! link

 

December 2021: New Group Member!

Heather Atkinson joins the group as a graduate student at WPI. Welcome Heather!

 

April 2021: New Group Members!

Dr. Mrinmoy Das and Dr. Leila Zamani join the group as postdoctoral researchers. Welcome to WPI!

 

February 2021: ChemRxiv Paper

Our work on C(sp3)–H fluorination with nucleophilic fluoride is up on ChemRxiv! Check it out! A collaborative effort with Pfizer.

 

February 2020

Yufei Zhang joins the group as a first-year graduate researcher at WPI. Welcome Yufei!

July 2019

Nicholas Fitzpatrick joins the group as a first-year graduate researcher at WPI. Welcome Nick!

 

July 2019

Musacchio Lab opens its doors!